1. What is the primary function of the cytoskeleton in cells?
a) Protein synthesis
b) Energy storage
c) Maintenance of cell shape and intracellular transport
d) DNA replication
Answer: c) Maintenance of cell shape and intracellular transport
2. Which cytoskeletal element is the thinnest?
a) Microtubules
b) Intermediate filaments
c) Microfilaments
d) Centrioles
Answer: c) Microfilaments
3. Microtubules are primarily composed of:
a) Actin
b) Tubulin
c) Keratin
d) Myosin
Answer: b) Tubulin
4. Actin filaments are crucial for:
a) DNA replication
b) Cellular movement and shape
c) Protein folding
d) Lipid synthesis
Answer: b) Cellular movement and shape
5. Which motor protein moves cargo along microtubules towards the minus end?
a) Kinesin
b) Dynein
c) Myosin
d) Actin
Answer: b) Dynein
6. The cytoskeleton is absent in:
a) Prokaryotic cells
b) Eukaryotic cells
c) Animal cells
d) Plant cells
Answer: a) Prokaryotic cells
7. The protein that forms microfilaments is:
a) Tubulin
b) Actin
c) Keratin
d) Lamin
Answer: b) Actin
8. Intermediate filaments provide:
a) Structural integrity
b) Intracellular transport
c) Cellular motility
d) Energy production
Answer: a) Structural integrity
9. Microtubules are organized by:
a) Mitochondria
b) Centrioles
c) Nucleus
d) Ribosomes
Answer: b) Centrioles
10. Kinesin moves vesicles towards which end of the microtubule?
a) Plus end
b) Minus end
c) Lateral end
d) No specific direction
Answer: a) Plus end
11. Cytoskeleton reorganization during cell division involves:
a) Nucleus
b) Spindle fibers
c) Golgi apparatus
d) Ribosomes
Answer: b) Spindle fibers
12. Which cytoskeletal element is involved in amoeboid movement?
a) Intermediate filaments
b) Microtubules
c) Microfilaments
d) Centrioles
Answer: c) Microfilaments
13. The cytoskeletal element responsible for flagellar movement is:
a) Microtubules
b) Actin filaments
c) Intermediate filaments
d) Collagen fibers
Answer: a) Microtubules
14. Which protein is associated with the sliding movement of actin filaments?
a) Dynein
b) Kinesin
c) Myosin
d) Tubulin
Answer: c) Myosin
15. The dynamic instability of microtubules is essential for:
a) DNA synthesis
b) Vesicle fusion
c) Cellular transport and division
d) Protein degradation
Answer: c) Cellular transport and division
16. The cytoskeletal network is anchored to the plasma membrane by:
a) Integrins
b) Tubulin
c) Actin filaments
d) Collagen
Answer: a) Integrins
17. The movement of cilia and flagella is powered by:
a) Myosin
b) Dynein
c) Kinesin
d) Actin filaments
Answer: b) Dynein
18. Intermediate filaments are composed of:
a) Actin
b) Keratin
c) Tubulin
d) Myosin
Answer: b) Keratin
19. Actin-binding proteins regulate:
a) Chromosome alignment
b) Microtubule dynamics
c) Actin filament assembly
d) Spindle formation
Answer: c) Actin filament assembly
20. Which cytoskeletal element forms the mitotic spindle?
a) Intermediate filaments
b) Microtubules
c) Microfilaments
d) Centrioles
Answer: b) Microtubules
21. Vesicle transport in neurons primarily uses:
a) Intermediate filaments
b) Actin filaments
c) Microtubules
d) Lysosomes
Answer: c) Microtubules
22. The stability of intermediate filaments makes them ideal for:
a) Transporting organelles
b) Providing tensile strength
c) Cell signaling
d) Cellular motility
Answer: b) Providing tensile strength
23. What facilitates endocytosis and exocytosis in cells?
a) Microtubules
b) Microfilaments
c) Intermediate filaments
d) Nuclear pores
Answer: b) Microfilaments
24. Microtubule growth occurs at:
a) Minus end
b) Plus end
c) Middle region
d) Both ends equally
Answer: b) Plus end
25. Which protein cross-links intermediate filaments?
a) Plectin
b) Dynein
c) Myosin
d) Kinesin
Answer: a) Plectin
26. The cytoskeleton interacts with organelles through:
a) Nucleotides
b) Motor proteins
c) Lipids
d) Cytoplasm
Answer: b) Motor proteins
27. Which component of the cytoskeleton resists compression?
a) Microtubules
b) Microfilaments
c) Intermediate filaments
d) Centrioles
Answer: a) Microtubules
28. The energy for cytoskeletal motor proteins is derived from:
a) GTP
b) ATP
c) NADH
d) FADH
Answer: b) ATP
29. Which process is not mediated by the cytoskeleton?
a) Chromosome segregation
b) Glycolysis
c) Vesicle transport
d) Cellular motility
Answer: b) Glycolysis
30. A cell lacking functional microtubules would be unable to:
a) Maintain cell shape
b) Transport organelles
c) Form spindle fibers
d) All of the above
Answer: d) All of the above