1. Basic Structure

  1. Which sugar is found in the structure of DNA?
    • A) Glucose
    • B) Ribose
    • C) Deoxyribose
    • D) Fructose
      Answer: C) Deoxyribose
  2. What type of sugar is present in RNA?
    • A) Ribose
    • B) Deoxyribose
    • C) Maltose
    • D) Sucrose
      Answer: A) Ribose
  3. How many strands does DNA have?
    • A) Single-stranded
    • B) Double-stranded
    • C) Triple-stranded
    • D) Quadruple-stranded
      Answer: B) Double-stranded
  4. What type of strand is RNA?
    • A) Single-stranded
    • B) Double-stranded
    • C) Helical
    • D) Circular
      Answer: A) Single-stranded
  5. Which nitrogenous base is unique to DNA?
    • A) Uracil
    • B) Adenine
    • C) Thymine
    • D) Cytosine
      Answer: C) Thymine

2. Nitrogenous Bases

  1. Which base in RNA pairs with adenine?
    • A) Thymine
    • B) Cytosine
    • C) Guanine
    • D) Uracil
      Answer: D) Uracil
  2. What are the four nitrogenous bases in DNA?
    • A) Adenine, Guanine, Uracil, Cytosine
    • B) Adenine, Thymine, Cytosine, Guanine
    • C) Thymine, Uracil, Adenine, Guanine
    • D) Uracil, Cytosine, Guanine, Thymine
      Answer: B) Adenine, Thymine, Cytosine, Guanine
  3. Which base is absent in RNA?
    • A) Thymine
    • B) Cytosine
    • C) Guanine
    • D) Uracil
      Answer: A) Thymine

3. Functions of DNA and RNA

  1. What is the primary function of DNA?
    • A) Protein synthesis
    • B) Genetic information storage
    • C) Energy production
    • D) Transport of molecules
      Answer: B) Genetic information storage
  2. What is the main function of RNA?
    • A) DNA replication
    • B) Genetic information storage
    • C) Protein synthesis
    • D) Energy transfer
      Answer: C) Protein synthesis
  3. Which type of RNA carries the genetic code from DNA?
    • A) mRNA
    • B) tRNA
    • C) rRNA
    • D) siRNA
      Answer: A) mRNA
  4. What does tRNA do in protein synthesis?
    • A) Stores genetic information
    • B) Carries amino acids to ribosomes
    • C) Translates RNA into DNA
    • D) Forms ribosomes
      Answer: B) Carries amino acids to ribosomes

4. Chemical Differences

  1. Which molecule is more chemically stable?
    • A) DNA
    • B) RNA
      Answer: A) DNA
  2. Why is RNA less stable than DNA?
    • A) Double-stranded structure
    • B) Ribose sugar has an extra hydroxyl group
    • C) No thymine base
    • D) Shorter length
      Answer: B) Ribose sugar has an extra hydroxyl group
  3. What type of bond connects nucleotides in both DNA and RNA?
    • A) Hydrogen bonds
    • B) Ionic bonds
    • C) Phosphodiester bonds
    • D) Peptide bonds
      Answer: C) Phosphodiester bonds

5. Types of RNA

  1. Which type of RNA is a structural component of ribosomes?
    • A) mRNA
    • B) rRNA
    • C) tRNA
    • D) miRNA
      Answer: B) rRNA
  2. Which RNA type regulates gene expression?
    • A) tRNA
    • B) rRNA
    • C) miRNA
    • D) mRNA
      Answer: C) miRNA

6. Biological Significance

  1. Why is DNA replication essential?
    • A) Energy production
    • B) Genetic material transmission to offspring
    • C) Protein modification
    • D) Nutrient metabolism
      Answer: B) Genetic material transmission to offspring
  2. What enables RNA to perform catalytic functions?
    • A) Its double-stranded nature
    • B) Its hydroxyl group
    • C) Its ability to form 3D structures
    • D) Its pairing with DNA
      Answer: C) Its ability to form 3D structures
  3. What is the significance of the uracil base in RNA?
    • A) Provides stability to RNA
    • B) Replaces thymine in RNA
    • C) Enhances protein synthesis
    • D) Increases replication rate
      Answer: B) Replaces thymine in RNA

7. Laboratory Applications

  1. Which technique is used to amplify DNA?
    • A) PCR (Polymerase Chain Reaction)
    • B) RT-PCR
    • C) Gel Electrophoresis
    • D) Western Blotting
      Answer: A) PCR (Polymerase Chain Reaction)
  2. Which process converts RNA back into DNA?
    • A) Transcription
    • B) Reverse Transcription
    • C) Translation
    • D) DNA replication
      Answer: B) Reverse Transcription
  3. Which molecule is studied in transcriptomics?
    • A) DNA
    • B) RNA
    • C) Proteins
    • D) Lipids
      Answer: B) RNA

8. Evolutionary Insights

  1. Which molecule is thought to have evolved first?
    • A) DNA
    • B) RNA
      Answer: B) RNA
  2. What hypothesis suggests RNA\u2019s early role in life?
    • A) Central Dogma Hypothesis
    • B) RNA World Hypothesis
    • C) Double Helix Hypothesis
    • D) Gene Theory
      Answer: B) RNA World Hypothesis

9. Key Comparisons

  1. Which is more prone to mutations?
    • A) DNA
    • B) RNA
      Answer: B) RNA
  2. Which molecule can self-replicate under experimental conditions?
    • A) DNA
    • B) RNA
      Answer: B) RNA
  3. Where is DNA primarily located?
    • A) Cytoplasm
    • B) Nucleus
    • C) Ribosomes
    • D) Cell membrane
      Answer: B) Nucleus
  4. Where is RNA found in the cell?
    • A) Nucleus
    • B) Cytoplasm
    • C) Ribosomes
    • D) All of the above
      Answer: D) All of the above
  5. What feature distinguishes DNA from RNA structurally and functionally?
    • A) Single vs. Double Strand
    • B) Stability and Longevity
    • C) Base Composition
    • D) All of the above
      Answer: D) All of the above

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