- Which of the following is a key characteristic of stem cells?
a) Limited differentiation ability
b) Self-renewal ability
c) Short lifespan
d) Inability to replicate
Answer: b) Self-renewal ability - What are embryonic stem cells derived from?
a) Bone marrow
b) Umbilical cord blood
c) Blastocyst-stage embryos
d) Adult tissues
Answer: c) Blastocyst-stage embryos - Which type of stem cells can differentiate into all cell types in the body?
a) Multipotent
b) Unipotent
c) Pluripotent
d) Oligopotent
Answer: c) Pluripotent - Induced pluripotent stem cells (iPSCs) are created by:
a) Extracting cells from the brain
b) Reprogramming adult cells to an embryonic-like state
c) Harvesting cells from the bone marrow
d) Extracting cells from the umbilical cord
Answer: b) Reprogramming adult cells to an embryonic-like state - Which of the following is a major ethical concern with embryonic stem cells?
a) Genetic mutations
b) High cost of research
c) Destruction of embryos
d) Limited availability
Answer: c) Destruction of embryos - Adult stem cells are primarily:
a) Totipotent
b) Pluripotent
c) Multipotent
d) Omnipotent
Answer: c) Multipotent - Which disease is most likely to benefit from stem cell therapy?
a) Common cold
b) Diabetes
c) Migraine
d) Hypertension
Answer: b) Diabetes - Stem cell therapy has shown promise in treating:
a) Heart disease
b) Spinal cord injuries
c) Parkinson’s disease
d) All of the above
Answer: d) All of the above - Which tissue has the highest concentration of adult stem cells?
a) Brain
b) Skin
c) Bone marrow
d) Liver
Answer: c) Bone marrow - What is the main advantage of using iPSCs over embryonic stem cells?
a) Cost-effectiveness
b) Reduced ethical issues
c) Greater differentiation potential
d) Longer lifespan
Answer: b) Reduced ethical issues - Totipotent stem cells are unique because they can:
a) Form any cell type except placental cells
b) Only form nerve cells
c) Develop into any cell type, including placental cells
d) Replicate for a limited time
Answer: c) Develop into any cell type, including placental cells - Which of these is NOT a source of stem cells?
a) Adipose tissue
b) Peripheral blood
c) Mitochondria
d) Umbilical cord blood
Answer: c) Mitochondria - Which regulatory body oversees clinical trials involving stem cells?
a) FDA
b) WHO
c) EPA
d) UNESCO
Answer: a) FDA - Stem cells used in regenerative medicine aim to:
a) Cure viral infections
b) Replace or repair damaged tissues
c) Enhance immune response
d) Prevent aging
Answer: b) Replace or repair damaged tissues - Which of the following best defines regenerative medicine?
a) Using artificial tissues to replace damaged organs
b) Using natural or lab-engineered stem cells to repair tissues
c) Relying solely on pharmaceuticals for treatment
d) Using radiation therapy for tissue repair
Answer: b) Using natural or lab-engineered stem cells to repair tissues - Which is a key application of mesenchymal stem cells (MSCs)?
a) Treating infections
b) Bone and cartilage repair
c) Skin grafting
d) Hormone replacement therapy
Answer: b) Bone and cartilage repair - What is the term for the process of creating new blood cells from stem cells?
a) Hematopoiesis
b) Osteogenesis
c) Neurogenesis
d) Angiogenesis
Answer: a) Hematopoiesis - A major limitation of adult stem cells is:
a) High ethical concerns
b) Limited differentiation potential
c) Risk of immune rejection
d) Lack of availability
Answer: b) Limited differentiation potential - Stem cells in the brain are primarily involved in:
a) Neurogenesis
b) Cardiogenesis
c) Angiogenesis
d) Hepatogenesis
Answer: a) Neurogenesis - Umbilical cord blood stem cells are particularly useful because:
a) They are abundant in iPSCs
b) They have no ethical concerns and are easily stored
c) They are only useful for the donor
d) They require embryonic tissue for collection
Answer: b) They have no ethical concerns and are easily stored - The ability of stem cells to replicate indefinitely is termed:
a) Multipotency
b) Self-renewal
c) Differentiation
d) Totipotency
Answer: b) Self-renewal - Which of the following diseases is being researched for treatment with neural stem cells?
a) ALS (Amyotrophic Lateral Sclerosis)
b) Type 2 Diabetes
c) Coronary artery disease
d) Hepatitis C
Answer: a) ALS (Amyotrophic Lateral Sclerosis) - Which factor influences stem cell differentiation?
a) Microenvironmental signals
b) Random mutations
c) Cell size
d) Blood type
Answer: a) Microenvironmental signals - Stem cell transplants often require:
a) Antibiotics
b) Immunosuppressive drugs
c) Radiation therapy
d) Genetic sequencing
Answer: b) Immunosuppressive drugs - Which is a direct application of hematopoietic stem cells?
a) Treating liver failure
b) Bone marrow transplants
c) Skin regeneration
d) Heart repair
Answer: b) Bone marrow transplants - What makes mesenchymal stem cells unique?
a) Only found in the brain
b) Ability to differentiate into connective tissues
c) Found only in embryos
d) Have no self-renewal capacity
Answer: b) Ability to differentiate into connective tissues - Stem cell differentiation is regulated by:
a) Genetic and environmental factors
b) Hormone levels only
c) Blood type compatibility
d) Cell cycle alone
Answer: a) Genetic and environmental factors - The ethical debate around stem cell research is mostly related to:
a) High financial costs
b) Use of adult stem cells
c) Use of embryonic stem cells
d) Lack of successful therapies
Answer: c) Use of embryonic stem cells - Which field is least likely to use stem cell technology?
a) Regenerative medicine
b) Robotics
c) Tissue engineering
d) Pharmacology
Answer: b) Robotics - Stem cell niches are:
a) Specialized environments that maintain stem cells
b) Locations in the bloodstream
c) Random clusters of damaged cells
d) Artificial structures for cell storage
Answer: a) Specialized environments that maintain stem cells
MCQs on Stem Cells: Potentials in Regenerative Medicine
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